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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PPP1R8
All Species:
40
Human Site:
S178
Identified Species:
73.33
UniProt:
Q12972
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q12972
NP_002704.1
351
38479
S178
T
A
H
N
K
R
I
S
T
L
T
I
E
E
G
Chimpanzee
Pan troglodytes
XP_001150604
378
41336
S178
T
A
H
N
K
R
I
S
T
L
T
I
E
E
G
Rhesus Macaque
Macaca mulatta
XP_001112289
378
41328
S178
T
A
H
N
K
R
I
S
T
L
T
I
E
E
G
Dog
Lupus familis
XP_865789
355
39236
S182
T
A
H
N
K
R
I
S
T
L
T
I
E
E
G
Cat
Felis silvestris
Mouse
Mus musculus
Q8R3G1
351
38509
S178
T
A
H
N
K
R
I
S
T
L
T
I
E
E
G
Rat
Rattus norvegicus
NP_001101381
351
38521
S178
T
A
H
N
K
R
I
S
T
L
T
I
E
E
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518825
234
26189
Q65
C
D
F
T
I
D
H
Q
S
C
S
R
V
H
A
Chicken
Gallus gallus
NP_001026062
354
38600
S179
T
A
H
N
K
R
I
S
T
L
T
I
E
E
G
Frog
Xenopus laevis
NP_001083528
346
37932
S175
T
A
H
N
K
R
I
S
T
L
T
I
E
E
G
Zebra Danio
Brachydanio rerio
NP_001094422
351
38384
S175
T
A
H
N
K
R
I
S
T
L
T
I
E
E
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_611177
383
42555
S167
T
A
H
N
R
R
I
S
M
L
G
I
D
D
D
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_492781
302
33933
D133
T
E
H
H
V
E
D
D
P
T
V
A
A
S
D
Sea Urchin
Strong. purpuratus
XP_001199058
347
38163
G174
T
V
H
N
K
R
I
G
A
I
G
F
D
E
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
91.8
91.2
89
N.A.
98
97.7
N.A.
65.8
88.6
82.9
77.7
N.A.
47.5
N.A.
39
51.5
Protein Similarity:
100
91.8
91.5
90.4
N.A.
98.5
98.5
N.A.
66
93.2
89.7
88
N.A.
62.1
N.A.
53.8
67.5
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
0
100
100
100
N.A.
60
N.A.
13.3
46.6
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
13.3
100
100
100
N.A.
80
N.A.
20
60
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
77
0
0
0
0
0
0
8
0
0
8
8
0
16
% A
% Cys:
8
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% C
% Asp:
0
8
0
0
0
8
8
8
0
0
0
0
16
8
16
% D
% Glu:
0
8
0
0
0
8
0
0
0
0
0
0
70
77
0
% E
% Phe:
0
0
8
0
0
0
0
0
0
0
0
8
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
8
0
0
16
0
0
0
70
% G
% His:
0
0
93
8
0
0
8
0
0
0
0
0
0
8
0
% H
% Ile:
0
0
0
0
8
0
85
0
0
8
0
77
0
0
0
% I
% Lys:
0
0
0
0
77
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
77
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% M
% Asn:
0
0
0
85
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
8
85
0
0
0
0
0
8
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
77
8
0
8
0
0
8
0
% S
% Thr:
93
0
0
8
0
0
0
0
70
8
70
0
0
0
0
% T
% Val:
0
8
0
0
8
0
0
0
0
0
8
0
8
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _